Pasteurella multocida as an Infectious Cause of Endocarditis

Pasteurella multocida endocarditis.

Rifampicin is a potent inducer of hepatic microsomal enzymes and increases the oxidation of cortisol to 63-hydroxycortisol.2 As the major pathway of cortisol metabolism involving tetrahydroreduction of the A ring is not thought to be altered this increased utilisation usually represents only a small percentage of the cortisol produced in patients with normal adrenal function. In patients with p...

Endocarditis caused by Pasteurella multocida.

Hydrogen Peroxide as an Effective Disinfectant for Pasteurella multocida

Pasteurella multocida (P. multocida) infections vary widely, from local infections resulting from animal bites and scratches to general infections. As of yet, no vaccine against P. multocida has been developed, and the most effective way to prevent pathogenic transmission is to clean the host environment using disinfectants. In this study, we identified which disinfectants most effectively inhi...

Pathogenomics of Pasteurella multocida.

The first complete genome sequence of the P. multocida avian isolate Pm70 was reported in 2001. Analysis of the genome identified many predicted virulence genes, including two encoding homologues of the Bordetella pertussis filamentous haemagluttinins, and genes involved in iron transport and metabolism. Availability of the genome sequence allowed for a range of whole-genome trans...

Pasteurella multocida infective endocarditis in an immunocompetent patient complicated by rhabdomyolysis and permanent hearing loss.

Pasteurella multocida is an inhabitant of the oral cavity of a variety of livestock and domestic pet species, especially cats and dogs. The case reported illustrates a 60-year-old, immunocompetent female patient who presented with P. multocida sepsis and aortic valve endocarditis. This required surgical bioprosthetic aortic valve replacement. Investigation also found infection-induced rhabdomyo...